A team lead by Osaka University researchers discovered a biological mechanism that inhibits colitis aggravation by regulating intestine levels of a microbial metabolite called adenosine triphosphate.
Luminal ATP, a type of ATP secreted by bacteria in the intestine, impacts the immune system of the host, the amount of luminal ATP is closely controlled to avoid intestinal inflammation.... https://www.coherentmarketinsights.com/news/a-new-discovery-of-ectoenzyme-that-hydrolyzes-atp-e-ntpd8-reduces-the-severity-of-colitis-511