Metabolic alterations associated with T2D are very well characterised by epidemiological and research primarily based studies. The pathogenesis and progression of T2D is ascribed to four mechanisms; greater Superior glycation finish product or service (AGE) formation, amplified polyol pathway flux, activation of protein kinase C (PKC) isoforms, and increased hexosamine https://www.directivepublications.org/journal-of-diabetology-research/