This mechanism might be throughout the induction of hepatic microsomal enzymes that metabolize the antibiotic. If phenobarbital and doxycycline are administered concurrently, the clinical reaction to doxycycline must be monitored intently. Phenytoin, sodium valproate, valproic acid: The influence of barbiturates within the metabolism of phenytoin seems to generally be variable. https://wardc332sep6.yomoblog.com/profile