To be able to rationalise the noticed ABL kinase inhibitory effects from the 3D structural point of view, the lead compounds I and II, and also the freshly created derivatives 4a, 4b, and five have been docked inside the catalytic kinase domains of BCR-ABLWT (PDB code: 3OXZ) and BCR-ABLT315I (PDB https://indazoleproducts42075.affiliatblogger.com/83260043/the-single-best-strategy-to-use-for-indazole-synthesis-review