These outcomes, together with a previous report showing that a small-molecule ACKR3 agonist CCX771 exhibits anxiolytic-like habits in mice,two aid the notion of focusing on ACKR3 as a unique solution to modulate the opioid procedure, which could open new therapeutic avenues for opioid-related Issues. Publishing this review implies that https://ellenc692dbd7.plpwiki.com/user