These final results, together with a earlier report displaying that a small-molecule ACKR3 agonist CCX771 exhibits anxiolytic-like conduct in mice,two guidance the principle of focusing on ACKR3 as a unique method to modulate the opioid technique, which could open up new therapeutic avenues for opioid-associated Issues. Submitting this review https://henryt738kzp2.hamachiwiki.com/user